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About Me and FoxyLogic

Personal Information:

My name is Mikkel Holmen Andersen, 37 year old and born in Aarhus, Denmark. Married and have two children.

I have a PhD in molecular and structural biology on the subject: receptor - ligand interactions. My main research interest is in protein chemistry. I have a strong background and experience with protein expression and purification, and with the subsequent aspects of protein characterisation by HPLC, sequencing, and mass spectrometry. I find special interest in the more technical parts of protein chemistry such as proteomics and bioinformatics.

I have done a 2-year post doc in Paris centred on chromatin modifying proteins involved in transcriptional regulation. I was involved in the purification and characterisation of a ~2 MDa protein complex from nuclear extracts of human cell lines.

Currently, I'm working as a scientist at Borean Pharma ApS, Aarhus, Denmark.

Other Interests:

I spend some of my time programming modules for instrument control. The Fermentor Control Program has the most focus and is continuously evolving as I and users get ideas to new features. The system includes an artificial intelligence control module (fuzzy logic and neural networks) to maximise product output. Currently the program is used by university departments, institutions and commercial users worldwide.

I also programmed a spectrophotometer data acquisition tool including a kinetic data analysis module, which is currently used in a biochemistry laboratory course at the Department of Molecular and Structural Biology, University of Aarhus, Denmark, some SQL Database tools to download and generate Access and MySQL databases of ~570.000 proteins including a query tool to datamine the databases, and server programs for automated database retrieval for local DNA and protein analysis tools.

Appointments:

2000: Short termed research position with PhD Andy Prescott, Department of Applied Genetics, John Innes Centre, Norwich, England.

2001: Post. Doc. position with M.D. PhD Laurence Zitvogel, UnitÚ d’Immunologie, Institut Gustave-Roussy, Villejuif, France.

2001- 2002: Post. Doc. position with M.D. PhD Marc Lipinski, Interactions moleculaires January 2003  et cancer - UMR 1598, Institut Gustave-Roussy, Villejuif, France.

2002 - 2007: Scientist at Borean Pharma A/S, Aarhus, Denmark.

Publications:

Hvarregaard, J., Andersen, M.H., Berglund, L., Rasmussen, J.T., and Petersen, T.E. (1996).
Characterization of glycoprotein PAS-6/7 from membranes of bovine milk fat globules.
Eur. J. Biochem. 240, 628-636.

Andersen, M.H., Berglund, L., Rasmussen, J.T., and Petersen, T.E. (1997). Bovine PAS-6/7
binds avb5 integrin and anionic phospholipids through two domains.
Biochemistry 18, 5441-5446.

Andersen, M.H. (1997). Characterization of two cellular binding domains in bovine PAS-6/7. M.Sc.-thesis, University of Aarhus.

Petersen, T.E., Rasmussen, L.K., Berglund, L., S°rensen, E.S., Rasmussen, J.T., Heegaard, C.W., Fedosov, S.N., Johnsen, L.B., Andersen, M.H., Larsen, L.B., and Benfeldt, C. (1999). Identification and characterization of new milk proteins. In: Dairy Science and Technology, pp. 194-199,
Proceedings of 25th International Dairy Congress, Aarhus, The Danish National Committee of IDF.

Nielsen, R.L., Andersen, M.H., Mabhout, P., Berglund, L., Petersen, T.E., and Rasmussen, J.T. (1999) Isolation of adipophilin and butyrophilin from bovine milk and characterization of a cDNA encoding adipophilin. J. Dairy Sci. 82, 2543-2549.

Andersen, M.H., Graversen, H., Fedosov, S.N., Petersen, T.E., and Rasmussen, J.T. (2000) Functional analyses of two cellular binding domains of bovine lactadherin.
Biochemistry. 39, 6200-6206.

Andersen M.H. (2000) Functional Analysis of bovine lactadherin's binding to integrin receptors and phospholipid membranes. PhD-thesis, University of Aarhus.

L. T. Pallesen, M. H. Andersen, R. L. Nielsen, L. Berglund, T. E. Petersen, L. K. Rasmussen, and J. T. Rasmussen. (2001) Purification of MUC1 from Bovine Milk-Fat Globules and Characterization of a Corresponding Full-Length cDNA Clone J. Dairy Sci. 84, 2591-2598.

Andre, F., Andersen, M., Wolfers, J., Lozier, A., Raposo, G., Serra, V., Ruegg, C., Flament, C., Angevin, E., Amigorena, S., Zitvogel, L. (2001) Exosomes in cancer immunotherapy: preclinical data.
Adv. Exp. Med. Biol. 495, 349-354.

Andersen, M.H., Berglund, L., Petersen, T.E., Rasmussen, J.T. (2002) Annexin-V Binds to the Intracellular Part of the beta(5) Integrin Receptor Subunit. Biochem. Biophys Res. Commun. 292, 550-557.

Westergaard U.B., Andersen M.H., Heegaard C.W., Fedosov S.N., Petersen T.E. (2003) Tetranectin binds hepatocyte growth factor and tissue-type plasminogen activator. Eur. J. Biochem. 270, 1850-1854.

About FoxyLogic:

FoxyLogic was born in 1997 but at this stage it is nothing more than a fancy name and logo to stick on the software that I have made.

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Last modified 07 februar 2008 09:50